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成果及论文

1. Cheng J* , Berninghausen O, Beckmann R*. A distinct assembly pathway of the human 39S late pre-mitoribosome. Nature communication,in press. *共同通讯 2. Su, T, Kudva, R, Becker, T, Buschauer, R, Komar, T, Berninghausen, O, Heijne, G, Cheng, J*, Beckmann, R*, Structural basis of L-tryptophan-dependent inhibition of Release Factor 2 by the TnaC arrest peptide, Nucleic Acids Research, in press. *共同通讯 3. Weng T, Steinchen W, Beatrix B, Berninghausen O, Becker T, Bange G, Cheng J* , Beckmann R*. Architecture of the active post-translational Sec translocon. EMBO J. 2021 Feb 1;40(3):e105643.*共同通讯 4. Wells JN, Buschauer R, Mackens-Kiani T, Best K, Kratzat H, Berninghausen O, Becker T, Gilbert W, Cheng J*, Beckmann R*. Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes. PLoS Biol. 2020 Jul 20;18(7):e3000780. *共同通讯 5. Lau B#, Cheng J#, Flemming D, La Venuta G, Berninghausen O, Beckmann R*, Hurt E*. Structure of the maturing 90S pre-ribosome in association with the RNA exosome. Mol Cell. 2021 Jan 21;81(2):293-303.e4. #共同第一 6. Cheng J#, Lau B#, La Venuta G, Ameismeier M, Berninghausen O, Hurt E*, Beckmann R*. 90S pre-ribosome transformation into the primordial 40S subunit. Science. 2020 Sep 18;369(6510):1470-1476. 7. Cheng J#, Ba?ler J#, Fischer P#, Lau B, Kellner N, Kunze R, Griesel S, Kallas M, Berninghausen O, Strauss D, Beckmann R*, Hurt E*, Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration. Mol Cell. 2019 Sep 19;75(6):1256-1269.e7. 8. Ameismeier M#, Cheng J#, Berninghausen O, Beckmann R. Visualizing late states of human 40S ribosomal subunit maturation. Nature. 2018 June 14; 558 :249-253.#共同第一 9. Cheng J, Kellner N, Berninghausen O, Hurt E, Beckmann R. 3.2-?-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage. Nat Struct Mol Biol. 2017 Nov;24(11):954-964. 10. Hu L#, Lu J#, Cheng J#, Rao Q, Li Z, Hou H, Lou Z, Zhang L, Li W, Gong W, Liu M, Sun C, Yin X, Li J, Tan X, Wang P, Wang Y, Fang D, Cui Q, Yang P, He C, Jiang H, Luo C, Xu Y. Structural insight into substrate preference for TET-mediated oxidation. Nature. 2015 Nov 5;527(7576):118-22.#共同第一 11. Hu L#, Li Z#, Cheng J#, Rao Q, Gong W, Liu M, Shi YG, Zhu J, Wang P, Xu Y. Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation. Cell. 2013 Dec 19;155(7):1545-55. #共同第一 12.Cheng J#, Yang H#, Fang J, Ma L, Gong R, Wang P, Li Z, Xu Y. Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation. Nat Commun. 2015 May 11;6:7023.